Buy SS-31 UK | SS-31 Peptide Pen 20mg

SS-31 (also known as Elamipretide or Bendavia) is a specialized mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2). It is supplied as a 20mg pre-filled, ready-to-use Genesis multi-dose research pen engineered for targeted cellular energy and cristae protection research.

Unlike general systemic antioxidants or central nervous system stimulants, SS-31 selectively concentrates within the inner mitochondrial membrane (IMM). It binds directly to cardiolipin to stabilize mitochondrial cristae structure and restore electron transport chain flow (Complex I-III), optimizing ATP cellular energy production without neural jitters or adrenal crashes.

In biohacking and longevity research, SS-31 is used as Step 1 (a 10 to 20-day primer cycle) to repair existing damaged mitochondrial membranes and stabilize cardiolipin ('fixing the engines'). Following SS-31 with MOTS-c (Step 2) activates AMPK and stimulates new mitochondrial biogenesis ('building new engines'). Researchers emphasize that building new mitochondria while existing ones are damaged is far less efficient.

SS-31 is an aromatic-cationic tetrapeptide incorporating modified structural amino acids (specifically 2',6'-dimethyltyrosine, or Dmt). Synthesizing and purifying this compound requires complex solid-phase peptide synthesis (SPPS) and rigorous HPLC testing to achieve ≥99% purity, making raw manufacturing costs considerably higher than simple linear peptides.

Clinical trial data (NIH/PubMed) show over 50% of subjects experience mild localized injection site reactions, including transient redness, itching, warmth, or swelling. This is a known localized vascular/histaminic response to the peptide molecule itself rather than a product defect. Scientific protocols recommend rotating subcutaneous administration sites across abdominal fat regions and allowing the solution to reach room temperature before use.

Human clinical trials for genetic mitochondrial diseases and renal ischemia evaluated high daily doses (10mg to 40mg daily via IV/SubQ). In grey-market exploratory research, researchers often utilize 1mg to 5mg/day micro-dosing or run short 10–20 day 20mg primer cycles, balancing cost considerations with cardiolipin binding efficiency.

SS-31 works at the organelle level inside cellular membranes rather than acting as a neurotransmitter stimulant. Noticeable laboratory markers focus on sustained baseline physical stamina, accelerated recovery from exercise/fatigue, and improved mental clarity over days rather than an instant caffeine-like rush.

Key research domains include Chronic Fatigue & Post-Viral/Long COVID recovery (addressing mitochondrial energy failure), Anti-Aging & Longevity (reversing age-related cristae degradation and curbing ROS), Cognitive Plasticity (restoring neural synaptic energy), and Multi-Organ Protection (cardiac, renal, and neural ischemia models).

No. The Genesis SS-31 pen arrives fully pre-filled and pre-formulated in a multi-dose 3ml cartridge with 12 disposable research needles. No manual powder mixing or bacteriostatic water is required.

The precision dial mechanism is calibrated as follows: 4 Clicks = 250mcg (0.25mg), 8 Clicks = 500mcg (0.50mg), 12 Clicks = 750mcg (0.75mg), and 16 Clicks = 1.0mg (1000mcg). Every 3 clicks represents a 100mcg dose increment.

Store refrigerated at 2°C to 8°C, protected from direct sunlight. Do not freeze.

No. SS-31 Peptide Pen 20mg is strictly for laboratory research, in vitro, and scientific trial purposes only. It is not approved for human consumption, self-administration, or medical diagnosis.