Retatrutide Dosage Calculator
Two ways to calculate a retatrutide research dose. Working from a vial? Convert mg → mL → U-100 syringe units below. Using a pre-filled Retaklik pen? Use the KLIK calculator — 6 KLIK = 1 mg on every pen. For laboratory research planning only.
Retatrutide (Retaklik) Pen Calculator — mg to KLIK
Selected Product
Retatrutide (RetaKlik) | 40mg | 60mg
Category: Weight Management · retaklik-40mg-60mg
Available pen sizes: 40mg, 60mg
0.1667 mg per KLIK · Total 240 KLIK / pen
Result
For 1 mg on the 40 mg pen, take 6 KLIKS.
0.1667 mg per KLIK · Actual: 1 mg
Note: Some pens have a max dial per dispensing cycle.
This is a math converter for research planning, not a human-use dosing tool.
Turn Your Retatrutide Calculator Result Into a Free Dosing Schedule
Use your calculator inputs to create a simple plan you can review, download, print, or add to your calendar, plus a free peptide guide.
What Your Free Retatrutide Schedule Includes
Your schedule organizes your calculator result into clear dose amounts, timing, vial estimates, and comparison details so it is easier to review and plan.
Retatrutide Research Schedule: Clinical Trial Escalation vs Community Calculator Trends
Compare published once-weekly retatrutide trial schedules with how researchers most commonly configure dose and frequency in calculator sessions.
Clinical Trial Frequency
- Once weekly dosing
- Phase 2 obesity trial reference
- Phase 3 TRIUMPH protocol
Clinical Trial Dose Range
- Starts at 1–2mg
- Steps up every 4 weeks
- Targets 8–12mg maintenance
Community Calculator Stats
- Most Common Dose: 2mg
- Top dose across 7,346 responses
- Crowd-sourced, not prescribed
| Stage / Week Range | Clinical Trial Reference Dose | Most Common Community Dose | Notes |
|---|---|---|---|
| Weeks 1–4 | 1–2mg | 2mg | Starting dose — monitor tolerance |
| Weeks 5–8 | 4mg | 2mg | First dose increase |
| Weeks 9–12 | 8mg | 2mg | Second dose increase |
| Maintenance | 8–12mg | 2mg | Maintenance dose range |
Clinical reference: Phase 2 obesity trial (Jastreboff et al., NEJM, 2023) and Phase 3 TRIUMPH protocol materials. Phase 2 used once-weekly dosing across multiple maintenance-dose groups; Phase 3 describes 2mg once weekly with step-ups every four weeks to target dose.
Retatrutide BAC Water Calculator Data
Live, crowd-sourced retatrutide calculator data from real anonymous inputs — standardized into clear ranges so you can compare common dose, BAC water, and weekly use patterns.
Calculations
30 days
Power of Many
When thousands of researchers run the same retatrutide math, reliable patterns start to show. This page reflects real calculator activity, not one person's opinion.
Anonymous Inputs
We only use the calculator math entered on the page — like vial size, BAC water, and target dose. No names, no emails, no accounts attached to the dataset.
No Corporate Bias
No company pays us to push a higher retatrutide dose, a certain reconstitution setup, or a specific product. The patterns come from user inputs only.
Retaklik Dosing Guide - mg to KLIK
On the MyReta 40mg Retaklik pen, 6 KLIK = 1 mg. On the 60mg Retaklik pen, 4 KLIK = 1 mg. Both pens contain 240 total KLIK. The maximum per dispensing cycle is 60 KLIK, which equals 10 mg on the 40mg pen and 15 mg on the 60mg pen.
How many clicks on a retatrutide pen? On a MyReta 40mg Retaklik pen, each KLIK equals about 0.1667 mg, so 1 mg = 6 KLIK. On a MyReta 60mg Retaklik pen, each KLIK equals 0.25 mg, so 1 mg = 4 KLIK. Both pens contain 240 total KLIK and the dial caps at 60 KLIK per cycle.
The mg per KLIK changes by pen size because the 40mg and 60mg pens both hold 240 total KLIK. The goal of this static table is to remove manual maths from research protocol planning and make the click count, dial-cycle limit, and pen duration easy to verify in plain HTML.
Retatrutide calculator formula: mg per KLIK = total pen mg / 240 KLIK. KLIK needed = target research amount in mg / mg per KLIK. Values are rounded to the nearest whole KLIK and checked against the 60 KLIK dispensing-cycle cap. This page is for laboratory research planning only; it is not a human-use dosing, injection, treatment, or medical-advice tool.
| Target mg | 40mg KLIK | 60mg KLIK | Doses / 40mg pen | Doses / 60mg pen |
|---|---|---|---|---|
| 0.5 mg | 3 KLIK | 2 KLIK | 80 | 120 |
| 1 mg | 6 KLIK | 4 KLIK | 40 | 60 |
| 2 mg | 12 KLIK | 8 KLIK | 20 | 30 |
| 2.5 mg | 15 KLIK | 10 KLIK | 16 | 24 |
| 3 mg | 18 KLIK | 12 KLIK | 13 | 20 |
| 4 mg | 24 KLIK | 16 KLIK | 10 | 15 |
| 5 mg | 30 KLIK | 20 KLIK | 8 | 12 |
| 6 mg | 36 KLIK | 24 KLIK | 6 | 10 |
| 8 mg | 48 KLIK | 32 KLIK | 5 | 7 |
| 10 mg | 60 KLIK (max on 40mg) | 40 KLIK | 4 | 6 |
| 12 mg | 72 KLIK (split) | 48 KLIK | 3 | 5 |
| 15 mg | 90 KLIK (split) | 60 KLIK (max on 60mg) | 2 | 4 |
Amounts above 60 KLIK exceed the single-cycle cap and should be treated as split-cycle research-planning values. Amounts-per-pen are rounded down to whole amounts.
Retatrutide Dosage Guide
Retatrutide is currently an investigational medicine. There is no approved dosage in the UK yet. The following information is based solely on Phase 3 clinical trials, where it is being studied as a once-weekly injection.
Key Points
- Not approved yet: Retatrutide is still being tested. There is no approved dose in the UK.
- Once a week: In major trials, participants received it as a once-weekly injection.
- Dose steps: The trials tested dose steps of 2mg, 4mg, 6mg, 9mg, and 12mg.
- Starting low: Participants started on 2mg a week. They slowly raised the dose every four weeks until they reached their target.
- Safety first: Do not buy retatrutide online or use it outside of an authorised clinical trial. Unlicensed products can be fake, illegal, or unsafe.
Clinical Trial Doses
The doses discussed here are based on clinical trials only. In the Phase 3 TRIUMPH programme, people usually started at 2mg once a week before increasing gradually every four weeks. The main dose steps tested are: 2mg, 4mg, 6mg, 9mg, and 12mg once weekly. These are trial doses, not approved prescribing doses. The correct dose and schedule may change if the medicine is approved in the future.
Trial Dosage Schedule
Retatrutide Dosage Chart (Trial Reference)
Important: This is for educational purposes only, as retatrutide is still investigational.
| Treatment Week | Weekly Dose | Purpose in Trials |
|---|---|---|
| Weeks 1-4 | 2mg | Starting dose – helps the body get used to it and cuts down early side effects. |
| Weeks 5-8 | 4mg | First step up – helps control appetite and improves metabolism. |
| Weeks 9-12 | 8mg | Second step up – linked to major weight loss in trials. |
| Weeks 13+ | 12mg | Top maintenance dose tested – gave the best average weight loss (about 28.7%). |
Starting & Maximum Doses
In the big trials, the starting dose is 2mg once a week. Doctors start participants on a low dose and plan to increase it every four weeks. This gives them time to watch for side effects. Participants slowly raise their dose until they hit their target (like 4mg, 9mg, or 12mg).
The highest dose tested in the big Phase 3 trials is 12mg once a week. The 12mg dose gave the most weight loss, but it also caused more stomach side effects.
Why is it increased slowly?
In trials, the dose goes up slowly to help the body adjust and to lower the chance of side effects. Medicines that work on gut hormones can cause stomach issues when starting out or when the dose goes up, like feeling sick (nausea), diarrhoea, or indigestion.
Raising the dose slowly gives trial doctors time to make sure the medicine is safe and easy to handle before moving to a bigger dose.
Phase 2 Clinical Trial Results
Retatrutide is still in Phase 3 trials, but the early Phase 2 results look very promising. In these trials, people taking the highest dose (12mg a week) lost an average of 24.2% of their starting body weight over 48 weeks. About 1 in 4 of these people lost at least 30% of their body weight.
Even the lower 4mg weekly dose showed great results in the trials. People lost an average of 17% of their weight over 48 weeks, and:
- 92% lost at least 5% of their weight.
- 75% lost at least 10% of their weight.
- 60% lost at least 15% of their weight.
Comparing Trial Results
Retatrutide vs Mounjaro
Mounjaro is already approved in the UK for weight loss and type 2 diabetes. Its active ingredient, tirzepatide, helps people lose an average of 22.5% of their weight over 72 weeks at its highest dose. Tirzepatide works by acting on two hormone receptors (GLP-1 and GIP). Retatrutide is different because it acts on three receptors.
Retatrutide vs Wegovy
Wegovy contains an ingredient called semaglutide. It acts on just one receptor (GLP-1) to slow down digestion and lower hunger. At its highest dose, Wegovy helps people lose an average of 21% of their weight over 72 weeks.
Side Effects Seen in Trials
The side effects reported in retatrutide trials are similar to those seen with Wegovy and Mounjaro. Most are mild or moderate stomach issues, such as feeling sick (nausea), diarrhoea, and constipation.
In the trials, these issues mostly happened when starting out or raising the dose. Participants managed them by eating smaller meals more often, avoiding spicy or greasy food, and sipping water often. A small number of trial participants (about 7%) felt changes in their skin, like tingling. These feelings were mild and did not make anyone stop the trial. Full safety details will be known once the Phase 3 trials are finished.
Retatrutide vs Tirzepatide (Mounjaro)
| Feature | Mounjaro | Retatrutide (Trial Data) |
|---|---|---|
| Active ingredient | Tirzepatide | Retatrutide |
| How it works | Works on two receptors (GLP-1 and GIP) to lower hunger and slow digestion. | Works on three receptors (GLP-1, GIP, and glucagon) to lower hunger, speed up fat burning, and slow digestion. |
| Available in the UK? | Yes, with a prescription. | No, still in Phase 3 trials. |
| Doses | 2.5mg to 15mg | 1mg to 12mg (in trials) |
| Common side effects | Feeling sick, diarrhoea, constipation, less appetite. | Similar side effects seen in trials. |
About Retaklik
Retaklik is a pre-filled research pen containing retatrutide (LY3437943), a triagonist of GLP-1, GIP, and glucagon receptors. Each pen contains 240 total KLIK, so mg per KLIK depends on the selected 40mg or 60mg pen size.
Acquire Retaklik
My Reta supplies Retaklik pens independently tested to 99%+ purity by Janoshik Analytical, with batch COAs available. UK next-day delivery.
View Retaklik pens →Janoshik verified · ≥99.0% HPLC · UK next-day
Other calculators
External Resources
Retatrutide Dosage Calculator: Vial Reconstitution & U-100 Syringe Units
Working from a lyophilised retatrutide research vial instead of a pre-filled pen? Enter your vial strength, BAC water, and target amount below — or use the reference table. For a 10 mg vial in 2 mL BAC water the concentration is 5 mg/mL, so a 2 mg research amount = 0.4 mL = 40 units on a U-100 syringe. Laboratory research planning only, not human-use dosing.
Draw 0.4 mL = 40 units on a U-100 syringe.
Concentration: 5 mg/mL · 2 mg ÷ 5 mg/mL = 0.4 mL · × 100 = 40 units. For laboratory research planning only.
The three retatrutide dosage formulas
- Concentration (mg/mL) = vial mg ÷ BAC water mL
- Draw volume (mL) = research amount (mg) ÷ concentration (mg/mL)
- U-100 units = draw volume (mL) × 100 (100 units = 1 mL)
Vial dosage table — 10 mg vial + 2 mL BAC water (5 mg/mL)
| Research amount | Draw volume | U-100 units |
|---|---|---|
| 0.5 mg | 0.1 mL | 10 units |
| 1 mg | 0.2 mL | 20 units |
| 2 mg | 0.4 mL | 40 units |
| 2.5 mg | 0.5 mL | 50 units |
| 4 mg | 0.8 mL | 80 units |
| 5 mg | 1.0 mL | 100 units |
Changing the BAC water volume changes the concentration, which changes the draw volume for the same mg amount — always recalculate with the formulas above.
Calculate a vial dose in three steps
- Concentration — 10 mg vial + 2 mL BAC water = 5 mg/mL.
- Draw volume — 2 mg ÷ 5 mg/mL = 0.4 mL.
- U-100 units — 0.4 mL × 100 = 40 units.
Prefer to skip reconstitution and syringe maths? MyReta Retaklik pens arrive pre-filled and pre-dosed — you dial KLIKs instead of measuring mL. Use the KLIK calculator above, or view the Retaklik pens (Janoshik-tested, ≥99% purity, UK next-day). Every calculator here is free — no subscription.
Frequently Asked Questions
How many KLIK is 1 mg on a Retaklik 40mg pen?
How many KLIK is 1 mg on a Retaklik 60mg pen?
What is the Retaklik calculator formula?
How many total KLIK are in each Retaklik pen?
How much is one KLIK on the Retaklik 40mg pen?
How much is one KLIK on the Retaklik 60mg pen?
How many KLIK is 2 mg on the Retaklik 40mg pen?
How many KLIK is 2 mg on the Retaklik 60mg pen?
How many KLIK is 2.5 mg on each Retaklik pen?
How many KLIK is 5 mg on each Retaklik pen?
How many KLIK is 10 mg on each Retaklik pen?
What is the maximum KLIK per dispensing cycle?
What happens if a calculated amount is more than 60 KLIK?
How many 1mg amounts are in a 40mg Retaklik pen?
How many 1mg amounts are in a 60mg Retaklik pen?
How many 2mg amounts are in a 40mg Retaklik pen?
How many 2mg amounts are in a 60mg Retaklik pen?
How many 5mg amounts are in a 40mg Retaklik pen?
How many 5mg amounts are in a 60mg Retaklik pen?
Which Retaklik pen sizes does this calculator support?
Why does this page include a static KLIK table?
Should I use the calculator or the static table?
What is Retaklik?
What is retatrutide?
Is this Retaklik calculator a medical dosing tool?
What is the usual retatrutide dosage?
What is the highest dose of retatrutide tested?
How often is retatrutide taken in trials?
Why do trial doses increase slowly?
How quickly is the dose increased in trials?
What is the maintenance dose in trials?
Can I take retatrutide 12mg?
How do I calculate a retatrutide dose from a vial?
How many units is 2 mg of retatrutide?
What are U-100 syringe units?
Do I need to recalculate if I change the amount of BAC water?
How much BAC water do I add to a 10 mg retatrutide vial?
What is bacteriostatic water?
This is a mathematical reference tool for laboratory research planning only. It is not a human-use dosing, injection, treatment, or medical-advice tool. MyReta accepts no responsibility for research decisions made using this tool.
How Does Retatrutide Compare?
Single, dual, and triple agonists side by side. Whichever compound fits your research, the last step is the same: turn a target dose into units on a syringe. Educational info only — always talk to your doctor!